%0 Journal Article %T 糖尿病鼠模型研究新进展 %T Progress in Diabetic Rat Model %A 陈郊丽 %A CHEN,Jiao-li, %J 昆明医科大学学报 %@ 1003-4706 %V 33 %N 2 %D 2012 %P - %K [关键词]糖尿病;动物模型;鼠 %K [Key words]Diabetes;Animal mode;Rat %X [摘要] 建立理想的动物模型是对糖尿病病因、发病机理及其药物治疗进行研究的重要途径.糖尿病鼠模型的制备方法可以分为自发性、实验性诱发模型、转基因模型等,各有其特点.对1、2型糖尿病鼠模型研究新进展做一综述 %X [Abstract]For an in-depth discussion on etiology,pathogenesis and drug treatment of diabetes,the establishment of the ideal diabetic animal model is an important way to undertake a study on diabetes mellitus. Preparation method can be divided into spontaneous diabetes mellitus rat model,induced by experimental models,transgenic and gene knockout models,each with its characteristic.This review will be an update to rat models of type 1 and type 2 diabetes mellitus in these years %R %U http://kmykdx.cnjournals.cn/ch/reader/view_abstract.aspx %1 JIS Version 3.0.0