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云南省不同地区产妇乙肝表面抗原筛查及乙肝病毒感染状况分析
昌思思1
昆明医学院
摘要:
[摘要]目的 了解云南省不同地区住院分娩产妇乙肝表面抗原(HBsAg)筛查水平和感染状况.方法 采用定额抽样方法,在全省16个州(市)中按乙肝报告发病率高、中、低分别抽取1个州(市),对所辖医院产科2011年1月~6月上报的产妇HBsAg筛查和感染现状进行分析.结果 云南省3州(市)的332所医院产科2011年1月~6月报告住院分娩产妇68 753人,HBsAg筛查率为97.44%,筛查方法以金标法为主,已筛查产妇中HBsAg阳性率2.35%,不同地区阳性率有一定差异(P<0.01),医院筛查阳性结果与省级复核的一致率较高(98.83%).在HBsAg阳性产妇中,农村产妇大三阳构成比高于城镇(P<0.05);15~29岁产妇大三阳构成比高于30~42岁组(P<0.01).结论 项目实施期间云南省不同地区HBsAg筛查率均较高;其次,金标法是云南省乡镇卫生院住院分娩孕妇HBsAg筛查的主要方法,筛查阳性结果可信,但存在一定漏检,故在条件允许的情况下对孕妇HBsAg的筛查和阳性标本的复核均需要选择敏感、稳定和成熟的ELISA法
关键词:  [关键词]产妇  HBsAg筛查  感染状况
DOI:
分类号:
基金项目:
Analysis on Hepatitis B Virus Surface Antigen Screening and Hepatitis B Virus Infection among Puerperants in Different Areas of Yunnan
CHANG Si-si
Abstract:
[Abstract]Objective To explore the hepatitis B virus surface antigen(HBsAg)screening and infection of hepatitis B virus(HBV)among puerperants giving birth to children in hospitals in different areas of Yunnan. Methods We selected three cities by quota sampling.Data about HBsAg screening and infection of HBV among puerperants were reported to local hospitals from January to June of 2011,the data in the three cities were collected and analyzed.Results The gold immunochromatography assay(GICA)was used by most hospitals for HBsAg screening ,a total of 68753 puerperants were reported by the 332 hospitals and the HBsAg screening rate was 97.44 %.The consistent rate of screening was 98.83 %. The positive rate in those who had screened for HBsAg was 2.35% and the positive rate among three areas showed significant difference(P<0.01).The constituent ratio of both HBsAg-and HBeAg -positive puerperants in villages was higher than that in cities(P<0.05).The constituent ratio of both HBsAg-and HBeAg-positive puerperants in 15~29 year-old group was higher than that in 30~42 year-old group(P<0.01).Conclusions The antepartum HBsAg screening rate is high among those who gave birth to children in hospitals.GICA is mainly used to do HBsAg screening in health centers in different area of Yunnan during the project.Although screening results are credible,the undetected rate exists.So HBsAg screening and retesting with sensitive,stable and mature ELISA method is a better choice
Key words:  [Key words]Puerperants  HBsAg Screening  Infection