| 摘要: |
| ［摘要］脑源性神经营养因子（brain-derived neurotrophic factor，BDNF） 对于神经元的生长、分化、存活、可塑性及损伤后的修复具有重要作用，能有效阻止甲基苯丙胺诱导神经元死亡．阐述了甲基苯丙胺毒性作用机制，BDNF生理作用及BDNF在甲基苯丙胺依赖机制中作用．BDNF在甲基苯丙胺依赖过程中可能起到重要的作用，对BDNF作用机制的研究将为甲基苯丙胺依赖机制和戒毒治疗提供理论依据． |
| 关键词: ［关键词］脑源性神经营养因子 甲基苯丙胺 依赖机制 |
| DOI： |
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| New Development in Role of BDNF in the Mechanism of Methamphetamine Dependence |
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LIU Ju－peng
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| Abstract: |
| ［Abstract］Brain-derived neurotrophic factor plays an important role in neuron growth, differentiation, survival, plasticity and damage repair, and it can effectively prevent the methamphetamine-induced neuronal death. The article describes the mechanism of the toxic effects of methamphetamine, BDNF physiological role, and the role of BDNF in methamphetamine-dependent mechanism. BDNF may play an important role in methamphetamine dependence. The clarification of role of BDNF in the methamphetamine-dependent mechanism may provide a theoretical basis for detoxification treatment. |
| Key words: ［Key words］Brain-derived neurotrophic factor Methamphetamine Dependent mechanism |