| 摘要: |
| ［摘要］ 目的 分析老年原发性高血压患者动态动脉硬化指数（AASI）与脉搏波传导速度（baPWV）、脉压指数（PPI）的关系，探讨这些指标在老年高血压患者动脉弹性评估中的意义． 方法 选择昆明医科大学附属延安医院2014 年5月至2015 年2月门诊及住院治疗的老年原发性高血压患者89例，分别进行动态血压检测和无创动脉硬化检测，采用Spearman分析AASI与baPWV、PPI的相关性．结果 本组89例研究对象中baPWV为（1 603.41±19.84）cm/s， AASI为（0.61±0.15），PPI为（0.44±0.06）．Spearman等级相关分析显示，AASI与平均舒张压呈负相关（r＝ -0.157，P＜O.05）．baPWV、PPI、平均脉压、平均收缩压与AASI呈正相关（r＝ 0.685、0.701、0.648、0.416，P＜O.01），且AASI与BaPWV、PPI的相关系数最高．结论 AASI可以反映动脉硬化的程度，随着AASI数值的增大，baPWV、PPI也随之增大． |
| 关键词: ［关键词］ 高血压 动脉硬化 脉搏波传导速度 |
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| 基金项目:［基金项目］ 云南省科技厅-昆明医科大学应用基础研究联合专项基金资助项目（2012FB098，2013FZ286） |
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| Correlation between AASI and baPWV, PPI in Elderly Patients with Essential Hypertension |
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SUN Yan
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（Dept. of Geriatrics，Affiliated Yan'an Hospital of Kunming Medical University，Kunming Yunnan 650051，China）
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| Abstract: |
| ［Abstract］Objective To investigate the relationship between the level of AASI and baPWV，PPI and explore the meaning of these indexes for arteriosclerosis assessment in elderly hypertensive patients. Methods Eighty-nine elderly essential hypertension patients who were outpatients and inpatients in our hospital were included in this study from May 2014 to February 2015. Ambulatory blood pressure monitoring and noninvasive arteriosclerosis detection were measured and the relationship between AASI and baPWV，PPI was also analyzed. Results The level of baPWV of 89 patients was（1603.41±19.84）cm/s，AASI was（0.61±0.15），and PPI was （0.44±0.06）. Spearman correlation analysis showed that AASI was negatively correlated with the average diastolic blood pressure（r = 0.157，P < 0.05）. BaPWV，PPI，mean arterial blood pressure and mean systolic blood pressure was positively correlated with AASI （r = 0.685，0.701，0.648，0.701，P < 0.01）. AASI，baPWV and PPI had higher correlation coefficient．Conclusion AASI can reflect the extent of atherosclerosis，and BaPWV and PPI may increase with the increase of AASI. |
| Key words: ［Key words］Hypertension Arteriosclerosis Pulse wave velocity |