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监测膝关节感染患者6种感染指标水平的临床意义
李 建1,2
1.(1)昆明医学院第一附属医院运动医学科,云南 昆明 650032;2.2)昆明医科大学临床技能中心,云南 昆明 650500)
摘要:
[摘要]目的 探讨膝关节感染患者中WBC、CRP、ESR、SAA、PCT、GR%的临床价值.方法 选取2012年3月至2015年1月间185例患者进行分析,根据细菌学结果将185例患者分为术前膝关节感染组(实验组)和术前术后均无膝关节感染组(对照组),其中实验组37例,对照组148例.收集临床数据,比较2组间术前及术后第1、3、7 天 WBC、CRP、ESR、SAA、PCT、GR%的差异.结果 术前实验组WBC、CRP、ESR、SAA、PCT、GR%均高于对照组,差异有统计学意义(P<0.05);在术后第1天实验组WBC、CRP、ESR、SAA均高于对照组,差异有统计学意义(P<0.05),而PCT、GR%在2组之间无明显差异(P>0.05);在术后第3天及第7天WBC、CRP、ESR、SAA、PCT、GR%在2组之间无明显差异(P>0.05).结论 WBC、CRP、ESR、SAA、PCT、GR%对于早期诊断、早期预防感染有良好的参考价值,可作为膝关节感染初筛检测指标.
关键词:  [关键词]感染  白细胞  超敏C反应蛋白  血沉  血清淀粉样蛋白  降钙素原  中性率细胞百分数
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基金项目:[基金项目]云南省科技厅-昆明医科大学应用基础研究联合专项基金资助项目(2012FB032)
Clinical Significance of 5 Infectious Indicators for Patients with Knee Infection
LI Jian1,2
1.(Dept. of Sport Medicine,First Affiliated Hospital of Kunming Medical University,Kunming Yunnan 650032;2.2)The Clinical Skill Trainning Center of Kunming Medical University,Kunming Yunnan 650500,China)
Abstract:
[Abstract]Objective To explore the clinical significance of white blood cell(WBC),C-reactive protein (CRP),Erythrocyte sedimentation rate(ESR),serum amyloid A(SAA),procalcitonin (PCT)and neutrophil granulocyte percentage(GR%)in patients with knee infection. Methods A retrospective study was conducted from March 2012 to January 2015. One hundred and eighty-five patients were collected in the study. They were divided into knee infection group(A,37 patients) and non-infection group(B,148 patients) according to the results of postoperative blood culture. The values of WBC, CRP, ESR, SAA,PCT and GR% were compared and analyzed between the two groups. Results The values of the 6 indicators in group A were higher than those in group B before operation,with statistically significant differences(P < 0.05). The values of WBC, CRP,ESR and SAA in group A were higher than those in group B on post-operation day 1(P < 0.05). However,PCT and GR% were no statistically significance between groups A and B(P > 0.05). The values of 6 indicators on post-operation days 3 and 7 were no statistically significance between the two groups(P > 0.05). Conclusion WBC,CRP,ESR,SAA,PCT and GR% showed good reference values for early diagnosis and prevention of infection,which can be used as the screen testing indexes in the early knee infection.
Key words:  [Key words]Infection  WBC  CRP  ESR  SAA  PCT  Neutrophil granulocyte percentage