| 摘要: |
| ［摘要］多发性骨髓瘤（multiple myeloma，MM）是一种恶性浆细胞单克隆增生性疾病，约占全部恶性肿瘤的1%，目前仍不能治愈，微小残留病是主要原因，因此，清除微小残留病，有可能治愈本病．在各种治疗方法中，针对多发性骨髓瘤的免疫基因疗法（Immune gene therapy 或 Immunogene therapy）是当今治疗的研究热点，近几年免疫基因疗法在体内外实验中取得了较好的结果，本文就免疫基因在多发性骨髓瘤治疗中的研究及应用进行综述. |
| 关键词: ［关键词］多发性骨髓瘤 免疫疗法 基因疗法 |
| DOI： |
| 分类号: |
| 基金项目:［基金项目］国家自然科学基金资助项目（81160074） |
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| The Research Progress of Immune Gene Therapy on the Treatment of Multiple myeloma |
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QIU Yu-zhen
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（Dept.of Hematology，The 2st Affiliated Hospital of Kunming Medical University，Kunming Yunnan 650101，China）
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| Abstract: |
| ［Abstract］Multiple myeloma （MM） is a malignant plasma cell disease， accounting for about 1% of all malignant tumors， is still uncurable， minimal residual disease（MRD） is the reason， therefore，removal of minimal residual disease maybe possible to cure the disease. In a variety of treatment methods， immune gene therapy for multiple myeloma is a hot research topic in recent years， has achieved good results in vitro and in vivo experiments， in this review immune genes therapy in multiple myeloma research would be discussed. |
| Key words: ［Key words］Multiple myeloma Immunotherapy Gene therapy |