| 摘要: |
| ［摘要］目的 分析患者临床随访数据和对患者抑郁状态的评估，探讨抑郁状态对维持性腹膜透析患者骨质疏松的影响．方法 纳入2014年01月至2015年06月在昆明医科大学第二附属医院肾内科就诊的维持性腹膜透析患者80例，记录患者一般资料和生化指标，并对全部患者进行骨密度检测判断是否发生骨质疏松，用抑郁自评量表（SDS）对患者的抑郁状态进行评价．结果 80名腹膜透析患者有34例（42.5%）存在骨质疏松，48例（60%）存在抑郁状态．Logistic回归分析显示，年龄、透析龄、性别、原发病是否糖尿病和抑郁状态是腹膜透析患者骨质疏松发生的影响因素，抑郁状态与腰椎、股骨颈T值呈负相关（分别r＝-0.347，r＝-0.426，P＜0.05）．结论 抑郁状态可能是腹膜透析患者发生骨质疏松的危险因素之一，临床上对腹膜透析患者骨质疏松的防治应注重心理干预． |
| 关键词: ［关键词］骨质疏松 抑郁 腹膜透析 骨密度 |
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| 基金项目:［基金项目］云南省教育厅科研基金资助项目（2015C031Y）；云南省内设研究机构科研项目（2014NS106） |
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| Effect of Depression on the Incidence of Osteoporosis in Patients with Maintenance Peritoneal Dialysis |
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BAI Yi-hua1,2,3
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1.（1）Dept. of Nephrology;2）Dept. of Endocrinology;3）Dept. of Orthopedics，The Second Affiliated Hospital of Kunming Medical University，Kunming Yunnan 650101，China）
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| Abstract: |
| ［Abstract］Objective To investigate the effect of depression on the incidence of osteoporosis in patients with maintenance peritoneal dialysis（MPD）. Methods We enrolled 80 MPD patients， who underwent peritoneal dialysis in our dialysis center. The clinical data and biochemical parameters of all patients were collected， bone mineral density was detected and the Self-rating depression scale was used to evaluate depression state. Results Among the 80 enrolled MPD patients， 34 patients had osteoporosis（42.5%）， 48 patients had the presence of depression（60%）. Logistic regression analysis showed that age， dialysis age， gender， diabetes history and depression state were the risk factors for osteoporosis in MPD patients， the depression state was negatively correlated with BMD of lumbar and femoral neck（r＝-0.347，r＝0.426，P＜0.05）. Conclusion Depression state may be a risk factor for osteoporosis in clinic， it is of great significance to focus on the psychological state of MPD patients in the prevention and treatment of osteoporosis. |
| Key words: ［Key words］Osteoporosis Depression Peritoneal dialysis Bone mineral density |