| 摘要: |
| ［摘要］目的 研究重型颅脑损伤患者围术期神经功能与红细胞免疫指标的变化情况．方法 选取2013年7月至2015年8月于西双版纳州人民医院进行手术治疗的40例重型颅脑损伤患者为观察组，同时采用40名同龄健康者为对照组，然后将观察组术前及术后1 d、3 d、5 d、7 d、10 d及14 d和对照组的神经功能相关指标与红细胞免疫指标进行比较．结果 观察组术前及术后1 d、3 d、5 d、7 d、10 d及14 d神经功能相关血清指标均高于对照组（P＜0.05），观察组术前及术后1 d、3 d、5 d、7 d、10 d的红细胞免疫指标均差于对照组（P＜0.05），术后5 d及7 d的红细胞免疫指标差于术前、术后1 d、3 d、10 d及14 d，P＜0.05．比较指标间均有显著性差异（P＜0.05）．结论 重型颅脑损伤患者围术期神经功能与红细胞免疫指标的变化较大，应给予此类患者上述指标以充分的监测及干预． |
| 关键词: ［关键词］重型颅脑损伤 围术期 神经功能 红细胞免疫指标 |
| DOI： |
| 分类号: |
| 基金项目:［基金项目］国家自然科学基金资助项目（81460174）；云南省科技厅-昆明医科大学应用基础研究联合专项基金资助项目(2013FB156) |
|
| Study on the Change of Nerve Function and Erythrocyte Immune Indexes of Patients with Severe Craniocerebral injury During the Perioperative Period |
|
FAN Shou-cheng1,2
|
|
1.（Dept. of Neurosurgery，People’s Hospital of Xishuang Ban’na Autonomous Prefecture，Jinghong Yunnan 666100;2）Dept. of Neurosurgery，The Second Affiliated Hospital of Kunming Medical University，Kunming Yunnan 650101，China）
|
| Abstract: |
| ［Abstract］Objective To study and observe the change of nerve function and erythrocyte immune indexes of patients with severe craniocerebral injury during the perioperative period. Methods Forty patients with severe craniocerebral injury treated with surgery in our hospital from July 2013 to August 2015 were selected as the observation group and 40 healthy persons with the same ages in the same period were selected as the control group. The nerve function related indexes and erythrocyte immune indexes of observation group before and at first，third，fifth，seventh，tenth and fourteenth day after the surgery and those of control group were compared. Results The serum nerve function related indexes of observation group before and at first，third，fifth，seventh，tenth and fourteenth day after the surgery were higher than those of control group. The erythrocyte immune indexes of observation group before and at first，third，fifth，seventh and tenth day after the surgery were worse than those of control group. The erythrocyte immune indexes at fifth and seventh day after the surgery were worse than those before and at first，third，third，tenth and fourteenth day after the surgery. The differences of comparison indexes were all significant（P＜0.05）. Conclusion The change of nerve function and erythrocyte immune indexes of patients with severe craniocerebral injury during the perioperative period are obvious. Those indexes should be paid with enough monitoring and intervention. |
| Key words: ［Key words］Severe craniocerebral injury Perioperative period Nerve function Erythrocyte immune indexes |