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长效无菌抗菌材料对鼻咽癌调强适形放疗后皮肤保护的效果观察
黄 华1
昆明医科大学第三附属医院,云南省肿瘤医院放射治疗中心
摘要:
[摘要]目的 观察长效无菌抗菌材料对鼻咽癌患者运用调腔适形放疗技术进行治疗后皮肤的保护作用.方法 将104例首次进行调腔适形放疗的鼻咽癌患者随机分为观察组和对照组56例,观察组在第1次放射治疗后预防性使用长效无菌抗菌材料喷洒局部皮肤,4次/d,对照组58例仅注意保持放射野皮肤清洁、干燥,2组均进行常规的皮肤护理和健康教育.结果 观察组和对照组Ⅱ、Ⅲ级放射性皮炎发生率为28.5%和66.7%;观察组放射性皮炎的发生程度明显轻于对照组,损伤发生的时间观察组也明显晚于对照组,差异均有统计学意义(P<0.05).结论 长效无菌抗菌材料能有效地预防放射性皮炎的发生,减轻皮肤损伤的程度、提高患者生活质量、保证放射治疗顺利进行.
关键词:  [关键词]调强适形放疗  放射损伤  皮肤保护
DOI:
分类号:
基金项目:
Long Acting Sterile Antibacterial Materials for Protecting Skin After Intensity Modulated Radiotherapy on Nasopharyngeal Carcinoma
HUANG Hua
Abstract:
[Abstract]Objective To observe the protective effect of long acting sterile antibacterial materials on skins of patients with nasopharyngeal carcinoma after intensity modulated radiotherapy(IMRT).Methods 104 patients with nasopharyngeal carcinoma who received first intensity modulated radiotherapy were randomly divided into 2 groups: the observation group and the control group.Long-acting sterile antibacterial material was prophylactically sprayed on local skins of 56 patients in observation group after the first radiotherapy for 4 times/day.48 patients in the control group were only given keeping clean and dry in the local skin. Patients in both groups were given routine skin care and health education.Results In the observation group and the control group,the incidence rate of Ⅱand Ⅲ radiodermatitis was 28.5% and 66.7%,respectively.The serious degree of radiodermatitis in patients in observation group was less than that in control group,and the incidence of radiodermatitis in patients in observation group was later than that in control group,and the difference was statistically significant(P<0.05).Conclusion Long acting antibacterial materials can effectively prevent the occurrence of radiodermatitis,reduce the degree of skin damage, improve the life quality of patients and ensure smooth accomplishment of radiation therapy.
Key words:  [Key words]Intensity modulated radiotherapy  Radiation injury  Protecting skin