| 摘要: |
| ［摘要］目的 探讨妇科患有肿瘤的患者在经过肿瘤切除术治疗后体内凝血功能的变化．方法 以曲靖市第一人民医院2013年8月至2014年12月收治的128名患有肿瘤的妇科患者为研究对象，将128名肿瘤妇科患者设为实验组，同时又以128名正常女性为对照组，对肿瘤患者在手术前后的血浆凝血酶原时间（ PT）、活化部分凝血活酶时间（APTT）、血浆凝血酶时间（TT）、血浆纤维蛋白原含量（ FIB）和D － 二聚体（ D － dimer） 水平以及肿瘤妇科患者与正常女性之间进行监测比较．结果 对比患者血浆凝血酶原时间（ PT）、活化部分凝血活酶时间（APTT）、血浆凝血酶时间（TT）、血浆纤维蛋白原含量（FIB）和D － 二聚体（ D － dimer）水平，可以明显发现手术前，实验组患者相较于对照组患者的各项指标都高，在手术完成之后，实验组患者的各项指标相较于实验组患者在手术前的各项指标都低．结论 妇科肿瘤患者在手术之前血浆凝血酶原时间（ PT）、活化部分凝血活酶时间（APTT）、血浆凝血酶时间（TT）、血浆纤维蛋白原含量（ FIB）和D － 二聚体（ D － dimer）水平高，妇科患者的凝血功能亢进，患者处于血栓前状态，通过监测患者体内凝血功能的各项指标，可以降低妇科患者在完成手术切除术发生血栓的发生率． |
| 关键词: ［关键词］妇科肿瘤 肿瘤切除术 凝血功能 |
| DOI： |
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| 基金项目:［基金项目］国家自然科学基金资助项目(81160035) |
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| Clinical Observation of the Changes of Blood Coagulation in Patients after Gynecological Tumor Surgery |
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HE Hong－fen
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（Dept. of Gynecology，The First People’s Hospital in Qujing City，Qujing Yunnan 655000，China）
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| Abstract: |
| ［Abstract］Objective To explore and analyze the clinical changes of blood coagulation in patients with gynecologic tumor after tumor resection. Method 128 patients with gynecologic cancer admitted in our hospital from August 2013 to December 2014 were taken as the research objects， these 128 patients with gynecologic tumor were selected as the experimental group，and meanwhile 128 normal women were selected as the control group. The plasma prothrombin time（PT），activated partial thromboplastin time（APTT）， thrombin time（TT），fibrinogen in blood（FIB）and D - dimer level（D-dimer）of the patients with gynecologic tumor before the surgery were monitored and compared with the ones after the surgery and a comparison was made between the patients with gynecologic tumor and the normal women. Results Through the comparison of the plasma prothrombin time（PT），activation activated partial thromboplastin time（APTT）， thrombin time（TT），fibrinogen in blood（FIB） and D - dimer （D - dimer） level of the patients，we found that before the surgery， each indicator of the patients in the experimental group was higher than the control group，after the completion of the surgery，each indicator of the patients in the experimental group was lower than before the surgery. Conclusions The plasma prothrombin time（PT），activated partial thromboplastin time（APTT），thrombin time（TT）， fibrinogen in blood（FIB）and D dimer （D-dimer）levels of the patients with Gynecological tumor patients are in a high level before the surgery，the gynecological patients have a hyperfunction of the blood coagulation，and the patients are in the prethrombotic state，through the monitoring of each indicator of blood coagulation in the patients，the incidence of thrombosis after the completion of the resection performed to the gynecological patients can be reduced . |
| Key words: ［Key words］Gynecological tumor Tumor resection Blood coagulation |