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骨质疏松症对骨性关节炎发病机制的影响
杨再英1,2
1.(1)昆明医科大学第一临床学院,云南 昆明 650500;2)昆明医科大学第一附属医院运动医学科,云南 昆明 650500)
摘要:
[摘要]目的 评估骨质疏松症对骨性关节炎发病机制的影响及分析骨质疏松症对骨性关节炎的发病是否存在相关性.方法 563例骨性关节炎患者及439例非骨性关节炎患者分别进行BMD、BMI、年龄统计分析.采用相关分析、R×Cχ2检验分析及方差分析方法,α=0.05.结果 病例组与对照组中OP率差异有统计学意义(P<0.01),病例组高于对照组.结论 OP患者患OA的危险是非OP患者的25.320倍,OP为OA发病机制影响因素.
关键词:  [关键词]骨性关节炎  发病机制  骨质疏松症
DOI:
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基金项目:[基金项目]云南省科技厅-昆明医科大学联合基金项目(2012FB032);昆明医科大学本科生创新研究基金(J12101006)
The Effect of Osteoporosis on the Pathogenesis of Osteoarthritis
YANG Zai-ying1,2
1.(1)The 1st Clinical Mdicine School,Kunming Medical University,Kunming Kunnan 650500;2)Dept. of Sports Medicine,The 1st Affiliated Hospital of Kunming Medical University,Kunming Yunnan 650500,China)
Abstract:
[Abstract]Objective To evaluate the effect of osteoporosis on the pathogenesis of osteoarthritis, and analyze the correlation of osteoporosis and osteoarthritis. Methods We statistically analyzed the data of 563 patients with osteoarthritis and 439 patients with osteoarthritis, including the bone mineral density,the method of statistics included relevance analysis,x2 of R×C form analysis and variance analysis.Results There was a statistically significant difference in the rate of osteoporosis between the case group and control group, the rate of osteoporosis in case group was higher than the control group. Conclusion The risk of osteoarthritis for osteoporosis patients is 25.320 times of the patients without osteoporosis, osteoporosis may be involved in the pathogenesis of osteoarthritis.
Key words:  [Key words]Osteoarthritis  Pathogenesis  Osteoporosis